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It plays an extremely important role in brain function, especially when it comes to the regulation of mood

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showed that xCT knockout in two different PDAC cell lines (MIA PaCa-2 and CAPAN-2) induces ferroptosis and significantly affects growth and proliferation in vitro and in vivo when injected subcutaneously in nude mice (126)

However, when skin is injured, stem cells are able to migrate from their niche and change their differentiation program, acquiring a high degree of plasticity [ 2 ]